ARHGAP20 polyclonal Antibody | BS60766

ARHGAP20 polyclonal Antibody | BS60766 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins. ARHGAP20 (Rho GTPase activating protein 20), also known as KIAA1391, is a 1,191 amino acid protein that contains one PH domain, one Ras-associating domain and one Rho-GAP domain. Expressed primarily in brain, but also present in lymph nodes and fetal liver, ARHGAP20 functions as a GTPase-activating protein for Rho-type GTPases, effectively converting Rho-type GTPases to an inactive, GDP-bound state. ARHGAP20 exists as multiple isoforms that are produced via alternative splicing. Chromosomal aberrations involving the ARHGAP20 gene are thought to be a cause of B-cell chronic lymphocytic leukemia (B-CLL) .

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ARHGAP20 polyclonal Antibody detects endogenous levels of ARHGAP20 protein.

Molecular Weight: ~ 133 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Rho GTPase-activating protein 20; Rho-type GTPase-activating protein 20; ARHGAP20; KIAA1391

Immunogen: A synthetic peptide corresponding to residues in Human ARHGAP20

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A