ARHGAP30 polyclonal Antibody | BS60757

ARHGAP30 polyclonal Antibody | BS60757 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form. ARHGAP30 (Rho GTPase activating protein 30), also known as Rho-type GTPase-activating protein 30, is a 1,101 amino acid protein that contains one Rho-GAP domain and exists as four alternatively spliced isoforms. Conserved in chimpanzee, dog, cow, mouse and rat, ARHGAP30 is among the most neurite-enriched GAPs, which also includes ARHGAP21, FNBP2 and Bcr) . One of four single-nucleotide polymorphisms (SNPs) at the USF-1 gene locus, rs2774279, which is located in the promoter area of the USF-1 gene, which is in turn located within its flanking gene ARHGAP30, is linked to low-density lipoprotein cholesterol levels, incident type 2 diabetes mellitus and increased cardiovascular risk.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ARHGAP30 polyclonal Antibody detects endogenous levels of ARHGAP30 protein.

Molecular Weight: ~ 119 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Rho GTPase-activating protein 30; Rho-type GTPase-activating protein 30; ARHGAP30

Immunogen: A synthetic peptide corresponding to residues in Human ARHGAP30

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: