ARHGAP39 Antibody | 6445

ARHGAP39 Antibody | 6445 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: ARHGAP39 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human ARHGAP39.
The immunogen is located within amino acids 880 - 930 of ARHGAP39.

Research Area: Neuroscience

Tested Application: E, WB

Application: ARHGAP39 antibody can be used for detection of ARHGAP39 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Specificiy: ARHGAP39 antibody is predicted to not cross-react with other RhoGAP protein family members.

Positive Control 1: Cat. No. 1288 - A20 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: ARHGAP39 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: ARHGAP39 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: ARHGAP39 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: ARHGAP39 Antibody: CrGAP, Vilse, KIAA1688, Rho GTPase-activating protein 39

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: ARHGAP39 Antibody: Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins. ARHGAP39 (Rho GTPase activating protein 39) is a 1, 083 amino acid nuclear protein that contains one MyTH4 domain, one Rho GAP domain and two WW domains. It is encoded by a gene located on human chromosome 8, which is associated with a variety of diseases and malignancies. ARHGAP39 regulates robo signaling and plays important roles in axon guidance.