ARHGEF11 Polyclonal Antibody | E-AB-16180

ARHGEF11 Polyclonal Antibody | E-AB-16180 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: ARHGB, ARHGEF 11, ARHGEF11, DKFZp667F1223, Glutamate transporter EAAT4 associated protein 48, GTRAP 48, GTRAP48, KIAA0380, OTTHUMP00000038716, OTTHUMP00000038717, PDZ RHOGEF, PDZ-RhoGEF, Rho guanine exchange factor (GEF) 11, Rho guanine nucleotide exchange factor (GEF) 11, Rho guanine nucleotide exchange factor 11, RhoA specific guanine nucleotide exchange factor, RhoGEF glutamate transport modulator

Application: WB, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Signal Transduction

Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.

Concentration: 0.8 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human ARHGEF11

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 168 kDa

Molecular Weight(Observed): N/A