ARMCX3 Antibody (C-term) [APR31695G]

ARMCX3 Antibody (C-term) [APR31695G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ARMCX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 299-325 amino acids from the C-terminal region of human ARMCX3.

Cellular Localisation: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8BHS6}; Single-pass membrane protein. Cytoplasm {ECO:0000250|UniProtKB:Q8BHS6}. Nucleus {ECO:0000250|UniProtKB:Q8BHS6}

Molecular Weight: 42501

Clone: Polyclonal

Gene Name: ARMCX3

Gene ID: 51566

Function: Regulates mitochondrial aggregation and transport in axons in living neurons. May link mitochondria to the TRAK2-kinesin motor complex via its interaction with Miro and TRAK2. Mitochondrial distribution and dynamics is regulated through ARMCX3 protein degradation, which is promoted by PCK and negatively regulated by WNT1. Enhances the SOX10-mediated transactivation of the neuronal acetylcholine receptor subunit alpha-3 and beta-4 subunit gene promoters.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Armadillo repeat-containing X-linked protein 3, ARM protein lost in epithelial cancers on chromosome X 3, Protein ALEX3, ARMCX3, ALEX3