ARN-272 | B2570

ARN-272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC₅₀ = 1.8 µM). It attenuates anandamide internalization and deactivation in vitro and in vivo respectively. Displays analgesic effects in rodent models of CB1-mediated nociceptive and inflammatory pain.

ARN-272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC₅₀ = 1.8 µM). It attenuates anandamide internalization and deactivation in vitro and in vivo respectively. Displays analgesic effects in rodent models of CB1-mediated nociceptive and inflammatory pain.

B2570 | ARN-272 DataSheet

Alternate Name/Synonyms: ARN 272, 4-[[4-(4-hydroxyphenyl)-1-phthalazinyl]amino]-N-phenyl-benzamide, ARN272

Appearance: Yellow solid

Formulation:

CAS Number: 488793-85-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₇H₂₀N₄O₂

Molecular Weight: 432.47

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities: >40 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: FAAH-like anandamide transporter (FLAT) inhibitor

MDL Number:

PubChem CID: 1386351

SMILES: C1=CC=C(C=C1)NC(=O)C2=CC=C(C=C2)NC3=NN=C(C4=CC=CC=C43)C5=CC=C(C=C5)O

InChi: InChI=1S/C27H20N4O2/c32-22-16-12-18(13-17-22)25-23-8-4-5-9-24(23)26(31-30-25)28-21-14-10-19(11-15-21)27(33)29-20-6-2-1-3-7-20/h1-17,32H,(H,28,31)(H,29,33)

InChi Key: UPKNGUQNXSMHBE-UHFFFAOYSA-N