BW
Arrestin-C (E374) polyclonal Antibody | BS2394
- SKU:
- BW-BS2394
- Availability:
- Usually ships in 5 working days
Description
Arrestin-C (E374) polyclonal Antibody | BS2394 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse
Application: WB IHC IF
Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Background: Arrestin-C, also known as retinal cone Arrestin-3, X-Arrestin or cArr, is a member of the Arrestin family of proteins. It is predominantly found in the retina and pineal gland and localizes to the inner and outer segments of red-, green- and blue-cone photoreceptors and the inner plexiform regions. Two Arrestin-C isoforms exist due to alternative splicing. Isoform 1 is the mature full length protein and isoform 2 is truncated, ending with an arginine for amino acid residue 359. Arrestin-C expression is stimulated by retinoic acid. It may play a role in retina-specific signal transduction and bind to photoactivated-phosphorylated red/green opsins. In addition, Arrestin-C forms homodimers and oligomers with β-Arrestins and may regulate β-Arrestin mediated signaling.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Arrestin-C (E374) polyclonal Antibody detects endogenous levels of Arrestin-C protein.
Molecular Weight: ~ 43 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Arrestin-C; Arrestin C; ArrestinC; Cone arrestin; C-arrestin; cArr; Retinal cone arrestin-3; X-arrestin; ARR3; ARRX; CAR
Immunogen: Synthetic peptide, corresponding to amino acids 350-400 of Human Arrestin-C.
Conjugate: N/A
Modification: N/A
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: N/A