ARSB Antibody | 7465

ARSB Antibody | 7465 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: ARSB antibody was raised against a 16 amino acid peptide near the carboxy terminus of human ARSB.
The immunogen is located within amino acids 460 - 510 of ARSB .

Research Area: Homeostasis

Tested Application: E, WB, IHC-P, IF

Application: ARSB antibody can be used for detection of ARSB by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: ARSB antibody is human, mouse and rat reactive. At least two isoforms of ARSB are known to exist; this antibody only recognizes the longest isoform.

Positive Control 1: Cat. No. 1412 - Mouse Lung Tissue Lysate

Positive Control 2: Cat. No. 1412 - Mouse Cerebellum Tissue Lysate

Positive Control 3: Cat. No. 10-101 - Human Lung Tissue Slide

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 59 kDa
Observed: 57kDa

Validation: N/A

Isoform: N/A

Purification: ARSB Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: ARSB Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: ARSB antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: ARSB Antibody : ASB, G4S, MPS6, Arylsulfatase B, N-acetylgalactosamine-4-sulfatase, ASB

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Aryl sulfatase B (ARSB) forms a homodimer that hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate (1) . ARSB localizes to the lysozyme as well as to the extracellular matrix (2) . Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B (3) , and can be treated with exogenous ARSB (4) .