ART1 Polyclonal Antibody | BS65729

ART1 Polyclonal Antibody | BS65729 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,

Application: IHC-P,

Application Range: IHC-P=1:100-500

Background: Phemx is a member of the tetraspanin (TM4SF) family of proteins that may be involved in transmembrane signal transduction, regulation of cell proliferation, differentiation and motility. Phemx is a multi-pass membrane protein containing intracellular N- and C-terminal domains, four transmembrane domains and two extracellular loops. It is ubiquitously expressed from early embryogenesis through adulthood. Phemx exhibits predominant expression in hematopoietic tissues suggesting a role in hematopoietic-cell function. In association with the Integrin αIIb/Integrin β3 complex, Phemx functions to stabilize arterial thrombi in platelets and regulate “outside-in” signaling. This interaction may be important in the process of wound healing. The gene encoding Phemx is located in an important tumor-suppressor gene region that has been associated with Beckwith-Wiedemann syndrome as well as a variety of cancers

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ART1 Polyclonal Antibody detects endogenous levels of ART1 protein.

Molecular Weight: 35kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ART 1; ART1; FLJ17158; FLJ97586; MGC22455; Pan hematopoietic expression; PHEMX; PHMX; tetraspanin 32; Tetraspanin; tetraspanin32; TSPAN32; TSSC6; Tumor suppressing STF cDNA 6; Tumor suppressing subchromosomal transferable fragment cDNA 6; Tumor suppressing subtransferable candidate 6.   

Immunogen: KLH conjugated synthetic peptide derived from human PHEMX/ART1:101-200/320 

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: