Ascomycin | 1573

Ascomycin (also known as Immunomycin) is an analog of tacrolimus with immunosuppressive, neurotrophic and antifungal activities. Ascomycin can be used to prevent rejection after an organ transplant, and to treat autoimmune diseases and skin diseases. Ascomycin inhibits the production of T helper type 1 and cytokines in target cells.

Ascomycin (also known as Immunomycin) is an analog of tacrolimus with immunosuppressive, neurotrophic and antifungal activities. Ascomycin can be used to prevent rejection after an organ transplant, and to treat autoimmune diseases and skin diseases.

1573 | Ascomycin DataSheet

Alternate Name/Synonyms: Immunomycin, FK-520, FR-520, FR900520, L683590

Appearance: Off-white solid

Formulation: N/A

CAS Number: 104987-12-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₄₃H₆₉NO₁₂

Molecular Weight: 792

Cell-Permeable?: Yes

Purity: ≥99%

Solubilities: DMSO or EtOH

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: An immunosuppressant

MDL Number: MFCD06198665

PubChem CID: 2241

SMILES: CCC1C=C(CC(CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC1=O)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC)C)C

InChi: InChI=1S/C43H69NO12/c1-10-30-18-24(2)17-25(3)19-36(53-8)39-37(54-9)21-27(5)43(51,56-39)40(48)41(49)44-16-12-11-13-31(44)42(50)55-38(28(6)33(46)23-34(30)47)26(4)20-29-14-15-32(45)35(22-29)52-7/h18,20,25,27-33,35-39,45-46,51H,10-17,19,21-23H2,1-9H3

InChi Key: ZDQSOHOQTUFQEM-UHFFFAOYSA-N