Aspartate Aminotransferase (AST, GOT), Human Liver | P1299

AST/SGOT is found in many tissues throughout the body, including the liver, heart, muscles, kidney, and brain. If any of these organs or tissues is affected by disease or injury, AST is released into the bloodstream. This means that AST isn't as specific an indicator of liver damage as ALT (also known as alanine aminotransferase, another type of enzyme found almost entirely in the liver). The ratio of AST and ALT levels are commonly used as biomarkers for liver health.

P1299 | Aspartate Aminotransferase AST GOT Human Liver DataSheet

Biomolecule/Target: Aspartate Aminotransferase (AST, GOT)

Synonyms: Aspartate Transaminase, Glutamate Oxaloacetate, AST, GOT, sGOT, AspAT, ASAT, serum glutamic oxaloacetic transaminase, AAT, Aspartate Aminotransferase (AST, GOT), Human Liver

Alternates names: Aspartate Transaminase, Glutamate Oxaloacetate, AST, GOT, sGOT, AspAT, ASAT, serum glutamic oxaloacetic transaminase, AAT

Taglines: Biomarkers for liver health.

NCBI Gene ID #: 2805

NCBI Gene Symbol: GOT1

Gene Source: Human

Accession #: P17174

Recombinant: No

Source: Human Liver

Purity by SDS-PAGEs: 90%

Assay: N/A

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: 1 U/mg (Dimension® Clinical Chemistry System)

Results: N/A

Binding Capacity: N/A

Unit Definition: One unit will catalyze the transamination of one micromole of L-aspartate to alpha-ketoglutarate forming L-glutamate and oxaloacetate per minute at 37°C and pH 7.8.Measured at 340 nm as one equimolar amount of NAD produced by a coupled reaction.

Molecular Weight: ~92 kDa

Concentration: N/A

Appearance: lyophilized

Physical form description: N/A

Reconstitution Instructions: 1 mg/mL in Tris buffered saline, 1% BSA, pH 8.0

Amino acid sequence: N/A