ASS1 Polyclonal Antibody | E-AB-18521

ASS1 Polyclonal Antibody | E-AB-18521 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Argininosuccinate synthase 1, Argininosuccinate synthase, Argininosuccinate synthetase 1, ASS, Ass-1, ass1, ASSA, ASSY, Citrulline aspartate ligase, Citrulline--aspartate ligase, CTLN1

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Metabolism, Signal Transduction

Background: ASS1 is a rate-limiting enzyme in the urea cycle. Citrullinemia type I is an autosomal recessive disorder that is caused by a deficiency of the urea cycle enzyme argininosuccinate synthetase (ASS1). Deficiency of ASS1 shows various clinical manifestations encompassing severely affected patients with fatal neonatal hyperammonemia as well as asymptomatic individuals with only a biochemical phenotype.

Concentration: 0.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human ASS1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 47 kDa

Molecular Weight(Observed): Refer to figures