800
ATF3 Antibody| F44888-0.08ML/F44888-0.4ML
- SKU:
- 800-F44888-0.08ML/800-F44888-0.4ML
- Availability:
- Usually ships in 5 working days
Description
ATF3 Antibody| F44888-0.08ML/F44888-0.4ML | Gentaur UK, US & Europe Distribution
Background: Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Isotype: Rabbit Ig
Species Reactivity: Human
Predicted Spacies Reactivity: Mouse, Rat, Bovine
Application: WB, FACS, ELISA
Application Details: Western blot: 1:1000, Flow Cytometry: 1:10-1:50
Application Note: Titration of the ATF3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Status: Available
Buffer: N/A
Limitation: This ATF3 antibody is available for research use only.
Purity: Antigen affinity
Immunogen: A portion of amino acids 140-168 from the human protein was used as the immunogen for this ATF3 antibody.
Storage: Aliquot the ATF3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Localization: N/A