BW
ATG12 (A98) polyclonal Antibody | AP0759
- SKU:
- BW-AP0759
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- Usually ships in 5 working days
Description
ATG12 (A98) polyclonal Antibody | AP0759 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC
Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200
Background: Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. The molecular machinery of autophagy was largely discovered in yeast and referred to as autophagy-related (Atg) genes. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ATG12 (A98) polyclonal Antibody detects endogenous levels of ATG12 protein.
Molecular Weight: ~ 20, 55 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Ubiquitin-like protein ATG12; Autophagy-related protein 12; APG12-like; ATG12; APG12; APG12L
Immunogen: Synthetic peptide, corresponding to Human ATG12.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Phosphoinosotode Signaling,Autophagy Signaling,