ATG5 Monoclonal Antibody | E-AB-22149

ATG5 Monoclonal Antibody | E-AB-22149 | Gentaur UK, US & Europe Distribution

Type: Monoclonal Antibody

Synonyms: APG 5, APG 5L, APG5, APG5 autophagy 5 like, APG5 like, APG5-like, APG5L, Apoptosis specific protein, Apoptosis-specific protein, ASP, ATG 5, Atg5, ATG5 autophagy related 5 homolog, ATG5, Autophagy protein 5, Autophagy related 5, hAPG5, Homolog of S Cerevisiae autophagy 5, OTTHUMP00000040507

Application: WB, IHC-p

Reactivity: Human, Mouse, Rat

Host: Mouse

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction

Background: Autophagy protein 5 is a protein that in humans is encoded by the ATG5 gene. It is an E3 ubiquitin ligase which is necessary for autophagy due to its role in autophagosome elongation. It is activated by ATG7 and forms a complex with ATG12 and ATG16L1. This complex is necessary for LC3-1 conjugation to PE to form LC3-II.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Protein of ATG5

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification Method: Protein A purification

Dilution: WB 1:500-2000, IHC 1:50-300

Clone: Clone:5D3

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): 55 kDa