ATIC monoclonal Antibody | MB62547

ATIC monoclonal Antibody | MB62547 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Monkey, Mouse, Rat, Dog

Application: FC, WB

Application Range: WB 1:500~2000, FLOW 1:100

Background: This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

Molecular Weight: 64.4 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: AICAR; AICARFT; HEL-S-70p; IMPCHASE; PURH

Immunogen: Full length human recombinant protein of human ATIC (NP_004035) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A