ATIC polyclonal Antibody | BS6973

ATIC polyclonal Antibody | BS6973 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB

Application Range: WB 1:500 - 1:2000

Background: The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities. AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, playing an important role in the production of nucleotides and IMP. Defects in the ATIC transformylase gene can cause AICA-rebsuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ATIC polyclonal Antibody detects endogenous levels of ATICprotein.

Molecular Weight: ~ 64 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase; AICAR transformylase2.IMP cyclohydrolase; ATIC; IMP synthase Inosinicase; PURH; AICAR; AICARFT; IMPCHASE

Immunogen: Recombinant full length Human ATIC.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: