ATP2B3 Antibody (C-term) [APR33067G]

ATP2B3 Antibody (C-term) [APR33067G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ATP2B3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1161-1194 amino acids from the C-terminal region of human ATP2B3.

Cellular Localisation: Cell membrane; Multi-pass membrane protein. Cell junction, synapse, presynaptic cell membrane {ECO:0000250|UniProtKB:Q64568}; Multi-pass membrane protein. Note=Localized at parallel fiber terminals {ECO:0000250|UniProtKB:Q64568}

Molecular Weight: 134197

Clone: Polyclonal

Gene Name: ATP2B3 {ECO:0000303|PubMed:8187550, ECO:0000312|HGNC:HGNC:816}

Gene ID: 492

Function: ATP-driven Ca (2+) ion pump involved in the maintenance of basal intracellular Ca (2+) levels at the presynaptic terminals (PubMed:25953895, PubMed:27035656, PubMed:22912398, PubMed:18029012) . Uses ATP as an energy source to transport cytosolic Ca (2+) ions across the plasma membrane to the extracellular compartment (PubMed:25953895, PubMed:27035656) . May counter-transport protons, but the mechanism and the stoichiometry of this Ca (2+) /H (+) exchange remains to be established (By similarity) .

Summary: Tissue Location: Highly expressed in the cerebellum (PubMed:8187550) . Expressed in adrenal glands (PubMed:27035656)

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB, IF

Dilution: IF--1:25 WB--1:2000

Synonyms: N/A