ATP6 polyclonal Antibody | BS1681

ATP6 polyclonal Antibody | BS1681 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: ATP6, also known as MT-ATP6, ATPASE6 or MTATP6, is a 226 amino acidmulti-passmembrane protein that localizestomitochondria and functions as a component of the F0 proton channel, playing a direct role in the transport of protons acrossthe mitochondrial membrane. Defectsin the gene encoding ATP6 are the cause of infantile bilateralstriatal necrosis, Leigh syndrome (LS),Leber hereditary optic neuropathy (LHON) and neurogenic muscle weakness, ataxia, and retinitis pigmentosa (NARP), all of which are neurological or retinal disorders. The gene encoding ATP6 exists as part of themitochondrial genome.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ATP6 polyclonal Antibody detects endogenous levels of ATP6 protein.

Molecular Weight: ~ 25 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ATP synthase subunit a; F-ATPase protein 6; Mtatp6; Atp6; Atpase6; mt-Atp6

Immunogen: A synthetic peptide corresponding to amino acids 55-70 of Mouse ATP6.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Regulation of Apoptosis,Hypoxia Signaling,Warburg Effect,Signaling Pathways Activating p38 MAP KinaseCell Cycle Control G1 S Checkpoint,Examples of Crosstalk Between Post-translational Modifications,Cell Cycle G2 M DNA Damage Signaling Pathway,