ATP6V1E1 Antibody | 19-150

ATP6V1E1 Antibody | 19-150 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 77-226 of human ATP6V1E1 (NP_001687.1) .

Research Area: Cancer, Signal Transduction

Tested Application: WB, IHC

Application: WB: 1:1000 - 1:2000
IHC: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: U-87MG

Positive Control 2: DU145

Positive Control 3: LO2

Positive Control 4: Mouse brain

Positive Control 5: Mouse kidney

Positive Control 6: Mouse liver

Molecular Weight: Observed: 35kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: ARCL2C, ATP6E, ATP6E2, ATP6V1E, P31, Vma4, V-type proton ATPase subunit E 1, ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1, H (+) -transporting two-sector ATPase, 31kDa subunit, H+-transporting ATP synthase chain E, vacuolar, V-ATPase 31 kDa subunit, V-ATPase subunit E 1, V-ATPase, subunit E, vacuolar proton pump subunit E 1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a component of vacuolar ATPase (V-ATPase) , a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome.