Atpenin A5 (Synthetic) | 2210

Synthetic. Originally isolated from Penicillium sp. strain. An antibiotic and antifungal agent. Potent and specific mitochondrial complex II (succinate-ubiquinone oxidoreductase) inhibitor and mitochondrial ATP-sensitive potassium (mK(ATP)) channel activator. Modulates mitochondrial ROS generation during cardioprotection.

Atpenin A5 is an antibiotic and antifungal agent. Potent and specific mitochondrial complex II (succinate-ubiquinone oxidoreductase) inhibitor and mitochondrial ATP-sensitive potassium (mK(ATP)) channel activator. Modulates mitochondrial ROS generation during cardioprotection.

2210 | Atpenin A5 (Synthetic) DataSheet

Alternate Name/Synonyms: 3-[(2S,4S,5R)-5,6-Dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy-2(1H)-pyridinone

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 119509-24-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₂₁Cl₂NO₅

Molecular Weight: 366.24

Cell-Permeable?: No

Purity: ≥95% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent mitochondrial complex II (succinate-ubiquinone oxidoreductase) inhibitor

MDL Number: N/A

PubChem CID: 54676868

SMILES: CC(CC(C)C(=O)C1=C(C(=C(NC1=O)OC)OC)O)C(CCl)Cl

InChi: InChI=1S/C15H21Cl2NO5/c1-7(9(17)6-16)5-8(2)11(19)10-12(20)13(22-3)15(23-4)18-14(10)21/h7-9H,5-6H2,1-4H3,(H2,18,20,21)/t7-,8-,9-/m0/s1

InChi Key: OVULNOOPECCZRG-CIUDSAMLSA-N