ATPIF1 Antibody (N-term) [APG02170G]

ATPIF1 Antibody (N-term) [APG02170G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ATPIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-35 amino acids from the N-terminal region of human ATPIF1.

Cellular Localisation: Mitochondrion.

Molecular Weight: 12249

Clone: Polyclonal

Gene Name: ATP5IF1 (HGNC:871)

Gene ID: 93974

Function: Endogenous F (1) F (o) -ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F (1) F (o) -ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F (1) F (o) -ATP synthase enzyme acts as an ATP hydrolase. Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: ATPase inhibitor, mitochondrial, Inhibitor of F (1) F (o) -ATPase, IF (1), IF1, ATPIF1, ATPI