Atractylenolide I | B2568

Atractylenolide I is a sesquiterpene that displays diverse biological activities, including anti-inflammatory, anti-angiogenic, anti-tumor, and antidepressant properties. It inhibits LPS-induced increases in TNF-α and nitric oxide (NO) production, as well as inducible nitric oxide synthase (iNOS) activity, in murine peritoneal macrophages (IC₅₀s = 23.1, 41, and 67.3 μM, respectively).

Atractylenolide I is a sesquiterpene that displays diverse biological activities, including anti-inflammatory, anti-angiogenic, anti-tumor, and antidepressant properties. It inhibits LPS-induced increases in TNF-α and nitric oxide (NO) production, as well as inducible nitric oxide synthase (iNOS) activity, in murine peritoneal macrophages (IC₅₀s = 23.1, 41, and 67.3 μM, respectively).

B2568 | Atractylenolide I DataSheet

Alternate Name/Synonyms: 4aS,5,6,7,8,8aS-hexahydro-3,8a-dimethyl-5-methylene-naphtho[2,3-b]furan-2(4H)-one, AO-I, ATL-1

Appearance: Crystalline solid

Formulation:

CAS Number: 73069-13-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₁₈O₂

Molecular Weight: 230.30

Cell-Permeable?: True

Purity: ≥98%

Solubilities: ~2 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A biologically active sesquiterpene

MDL Number: MFCD09037395

PubChem CID: 5321018

SMILES: CC1=C2CC3C(=C)CCCC3(C=C2OC1=O)C

InChi: InChI=1S/C15H18O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h8,12H,1,4-7H2,2-3H3/t12-,15+/m0/s1

InChi Key: ZTVSGQPHMUYCRS-SWLSCSKDSA-N