ATRIP polyclonal Antibody | BS8739

ATRIP polyclonal Antibody | BS8739 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IP

Application Range: WB 1:500 - 1:2000 IP 1:50 - 1:200

Background: The product of the ATRIP gene is an essential component of the DNA damage checkpoint, and binds to single stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ATRIP polyclonal Antibody detects endogenous levels of ATRIP protein.

Molecular Weight: ~ 86kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ATR-interacting protein; ATM and Rad3-related-interacting protein; ATRIP; AGS1

Immunogen: Recombinant full length Human ATRIP.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: