ATRN Antibody (N-term) [APG02173G]

ATRN Antibody (N-term) [APG02173G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ATRN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-66 amino acids from the N-terminal region of human ATRN.

Cellular Localisation: [Isoform 1]: Cell membrane; Single-pass type I membrane protein [Isoform 3]: Secreted

Molecular Weight: 158537

Clone: Polyclonal

Gene Name: ATRN

Gene ID: 8455

Function: Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity) . Has a critical role in normal myelination in the central nervous system (By similarity) .

Summary: Tissue Location: Isoform 2 is detected in plasma (at protein level) . Expressed and secreted by activated T-lymphocytes. Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very low levels found in thymus. Isoform 2 is the major isoform in peripheral blood leukocytes

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Attractin, DPPT-L, Mahogany homolog, ATRN, KIAA0548, MGCA