ATXN2 Antibody (Center) [APG03178G]

ATXN2 Antibody (Center) [APG03178G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ATXN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 725-757 amino acids from the Central region of human ATXN2.

Cellular Localisation: Cytoplasm.

Molecular Weight: 140283

Clone: Polyclonal

Gene Name: ATXN2

Gene ID: 6311

Function: Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane.

Summary: Tissue Location: Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Ataxin-2, Spinocerebellar ataxia type 2 protein, Trinucleotide repeat-containing gene 13 protein, ATXN2, ATX2, SCA2, TNRC13