ATXN2L Antibody (C-term) [APR32134G]

ATXN2L Antibody (C-term) [APR32134G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This ATXN2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1021-1048 amino acids from the C-terminal region of human ATXN2L.

Cellular Localisation: Membrane; Peripheral membrane protein. Cytoplasm. Nucleus speckle. Cytoplasmic granule. Note=Predominantly cytoplasmic but is also detected in nuclear speckles (PubMed:23209657) . Component of cytoplasmic stress granules (PubMed:23209657) . Inhibition of methylation alters nuclear localization (PubMed:25748791) . Methylation does not seem to be required for localization to stress granules under stress conditions (PubMed:25748791) .

Molecular Weight: 113374

Clone: Polyclonal

Gene Name: ATXN2L

Gene ID: 11273

Function: Involved in the regulation of stress granule and P-body formation.

Summary: Tissue Location: Expressed at high levels in thymus, lymph node, spleen, fetal kidney and adult testis. Constitutively associated with MPL and EPOR in hematopoietic cells.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, FC

Dilution: WB--1:1000 FC--1:10~50

Synonyms: Ataxin-2-like protein, Ataxin-2 domain protein, Ataxin-2-related protein, ATXN2L, A2D, A2LG, A2LP, A2RP