Aurintricarboxylic acid | 1506

Inhibits apoptosis in various cell types induced by a variety of factors. Potent inhibitor of DNA topoisomerase II in vitro and protein-nucleic acid interactions. Stimulates the tyrosine phosphorylation of MAP kinases. Inhibits major calpain isoforms.

Aurintricarboxylic acid (ATA) Inhibits apoptosis in various cell types induced by a variety of factors. Potent inhibitor of DNA topoisomerase II in vitro and protein-nucleic acid interactions. Stimulates the tyrosine phosphorylation of MAP kinases.

1506 | Aurintricarboxylic acid DataSheet

Alternate Name/Synonyms: ATA

Appearance: Red-brown solid

Formulation: N/A

CAS Number: 4431-00-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₁₄O₉

Molecular Weight: 422.4

Cell-Permeable?: No

Purity: >85%

Solubilities: 1 M NH₄OH (10 mg/ml)

Handling: Protect from light and air

Country of Origin: USA

Tag Line: A DNA topoisomerase II inhibitor

MDL Number: MFCD00011663

PubChem CID: 2259

SMILES: C1=CC(=C(C=C1C(=C2C=CC(=O)C(=C2)C(=O)O)C3=CC(=C(C=C3)O)C(=O)O)C(=O)O)O

InChi: InChI=1S/C22H14O9/c23-16-4-1-10(7-13(16)20(26)27)19(11-2-5-17(24)14(8-11)21(28)29)12-3-6-18(25)15(9-12)22(30)31/h1-9,23-24H,(H,26,27)(H,28,29)(H,30,31)

InChi Key: GIXWDMTZECRIJT-UHFFFAOYSA-N