Avian A Screening & Avian H5N1 Typing FRT (CE) | R-V33-FRT

Avian A Screening & Avian H5N1 Typing FRT | R-V33-FRT is available for delivery

Description:

General information: Real Time PCR test for detection of Avian A virus and genotyping for H5N1

Target Disease Type: Respiratory Infections

Specific Application: Influenza

Storage and Shipping : on request

INTRODUCTION

Avian influenza is an infectious disease of birds caused by type A strains of the influenza virus. The disease, which was first identified in Italy more than 100 years ago, occurs worldwide. All birds are thought to be susceptible to infection with avian influenza, though some species are more resistant to infection than others. Infection causes a wide spectrum of symptoms in birds, ranging from mild illness to a highly contagious and rapidly fatal disease resulting in severe epidemics. The latter is known as “highly pathogenic avian influenza”. This form is characterized by sudden onset, severe illness, and rapid death, with a mortality that can approach 100%.

Of the 15 avian influenza virus subtypes, H5N1 is of particular concern for several reasons. H5N1 mutates rapidly and has a documented propensity to acquire genes from viruses infecting other animal species. Its ability to cause severe disease in humans has now been documented in many cases. In addition, laboratory studies have demonstrated that isolates from this virus have a high pathogenicity and can cause severe disease in humans.

INTENDED USE

Avian A Screening & H5N1Typing FRT is Real-Time amplification test for the qualitative detection of Avian influenza A virus RNA in clinical specimens and genotyping of positive samples for H5N1 subtype.

PRINCIPLE OF ASSAY

Avian A Screening & H5N1Typing FRT RG Test is based on four major processes: isolation of Avian influenza A virus RNA from specimens, reverse transcription of the RNA, Real Time amplification of the cDNA of Avian influenza A virus with subsequent identification of subtype Н5N1.