AZ-7371 | B2294

AZ-7371 is a non-covalent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1) with an IC₅₀ value of 10 nM. It also inhibits PDE6 (IC₅₀ = 4 µM).

AZ-7371 is a non-covalent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1) with an IC₅₀ value of 10 nM. It also inhibits PDE6 (IC₅₀ = 4 µM).

B2294 | AZ-7371 DataSheet

Alternate Name/Synonyms: N-(2-hydroxyethyl)-1-((6-methoxy-5-methylpyrimidin-4-yl)methyl)-6-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxamide; DprE1-IN-1

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1494675-86-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₂₁N₅O₃

Molecular Weight: 355.4

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A non-covalent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1)

MDL Number: N/A

PubChem CID: 72792692

SMILES: CC1=CC2=C(C(=CN2CC3=C(C(=NC=N3)OC)C)C(=O)NCCO)N=C1

InChi: InChI=1S/C18H21N5O3/c1-11-6-15-16(20-7-11)13(17(25)19-4-5-24)8-23(15)9-14-12(2)18(26-3)22-10-21-14/h6-8,10,24H,4-5,9H2,1-3H3,(H,19,25)

InChi Key: VDRYGTNDKXIPSK-UHFFFAOYSA-N