Description
AZD-1283 is a potent antagonist of the P2Y12 receptor. In a modified Folts model in dog, AZD-1283 dose-dependently induces increases in blood flow and inhibition of ADP-induced platelet aggregation with antithrombotic ED₅₀ value of 3.0 μg/kg/min.
AZD-1283 is a potent antagonist of the P2Y12 receptor. In a modified Folts model in dog, AZD-1283 dose-dependently induces increases in blood flow and inhibition of ADP-induced platelet aggregation with antithrombotic ED₅₀ value of 3.0 μg/kg/min.
Alternate Name/Synonyms: Ethyl 6-(4-((benzylsulfonyl)carbamoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 919351-41-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₃H₂₆N₄O₅S
Molecular Weight: 470.54
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent P2Y12 receptor antagonist
MDL Number: N/A
PubChem CID: 23649325
SMILES: COC(=O)C1=C(N=C(C(=C1)C#N)N2CCC(CC2)C(=O)NS(=O)(=O)CC3=CC=CC=C3)C
InChi: InChI=1S/C23H26N4O5S/c1-3-32-23(29)20-13-19(14-24)21(25-16(20)2)27-11-9-18(10-12-27)22(28)26-33(30,31)15-17-7-5-4-6-8-17/h4-8,13,18H,3,9-12,15H2,1-2H3,(H,26,28)
InChi Key: NEMHKCNXXRQYRF-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |
