AZD-4635 | B2012

AZD-4635 is an orally available, small molecule adenosine A2A receptor antagonist. It reverses adenosine-mediated T-cell suppression and enhances antitumor immunity.

AZD-4635 is an orally available, small molecule adenosine A2A receptor antagonist. It reverses adenosine-mediated T-cell suppression and enhances antitumor immunity.

B2012 | AZD-4635 DataSheet

Alternate Name/Synonyms: 6-(2-chloro-6-methylpyridin-4-yl)-5-(4-fluorophenyl)-1,2,4-triazin-3-amine; HTL-1071

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1321514-06-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₁₁ClFN₅

Molecular Weight: 315.74

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A small molecule adenosine A2A receptor antagonist

MDL Number: N/A

PubChem CID: 86676119

SMILES: CC1=NC(=CC(=C1)C2=C(N=C(N=N2)N)C3=CC=C(C=C3)F)Cl

InChi: InChI=1S/C15H11ClFN5/c1-8-6-10(7-12(16)19-8)14-13(20-15(18)22-21-14)9-2-4-11(17)5-3-9/h2-7H,1H3,(H2,18,20,22)

InChi Key: NCWQLHHDGDXIJN-UHFFFAOYSA-N