Additional Information
Short Description: |
ERK kinase inhibitor |
Research Area: |
Cell Signaling, Cancer, Apoptosis, Cancer Growth Inhibitors, Tyrosine Kinase Inhibitors |
Alternative Name(s): |
Selumetinib, AZD6244, 6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide |
Category: |
Small Molecules |
Product Type: |
Inhibitor |
CAS No.: |
606143-52-6 |
Molecular Formula: |
C17H15BrClFN4O3 |
Molecular Weight: |
457,7 |
Source: |
Synthetic |
Purity: |
≥98% |
Solubility: |
Soluble in DMSO (92 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C) |
Appearance: |
White to off-white solid |
Storage: |
-20ºC |
Shipping: |
Shipped Ambient |
SMILES: |
CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO |
InChI: |
InChI=1S/C17H15BrClFN4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26) |
InChIKey: |
CYOHGALHFOKKQC-UHFFFAOYSA-N |
Field of Use: |
For in vitro research use only. |
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