Additional Information
Short Description: |
ERK kinase inhibitor |
Research Area: |
Cell Signaling, Cancer, Apoptosis, Cancer Growth Inhibitors, Tyrosine Kinase Inhibitors |
Alternative Name(s): |
Selumetinib, AZD6244, 6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide |
Category: |
Small Molecules |
Product Type: |
Inhibitor |
CAS No.: |
606143-52-6 |
Molecular Formula: |
C17H15BrClFN4O3 |
Molecular Weight: |
457,7 |
Source: |
Synthetic |
Purity: |
≥98% |
Solubility: |
Soluble in DMSO (92 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C) |
Appearance: |
White to off-white solid |
Storage: |
-20ºC |
Shipping: |
Shipped Ambient |
SMILES: |
CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO |
InChI: |
InChI=1S/C17H15BrClFN4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26) |
InChIKey: |
CYOHGALHFOKKQC-UHFFFAOYSA-N |
Field of Use: |
For in vitro research use only. |
Related Products
AZD6244 | 2234
26
NULL601.00
Cell-permeable. A potent, highly selective and non-ATP competitive inhibitor of mitogen-activated protein kinase kinase 1/2 (MEK1/2) (IC₅₀ = 14 nM/L against purified MEK1). Displays antineoplastic...
26-2234-GEN
HIV Seroconversion Panel Donor# 61694-74 13 X 1 mL
2
NULL1,949.00
HIV Seroconversion Panel Donor# 61694-74 (13 X 1 mL)
2-HIV6244-GEN
MIF Rabbit Polyclonal Antibody | ES6244
855
NULL444.00 - NULL528.00
MIF Rabbit Polyclonal Antibody | ES6244 | Gentaur UK, US & Europe Distribution Alternative Names: MIF; GLIF; MMIF; Macrophage migration inhibitory factor; MIF; Glycosylation-inhibiting...
855-ES6244-GEN