AZD9496 | B1652

AZD9496 is a potent and orally bioavailable selective estrogen receptor down regulator (Ki=0.7 nM) and antagonist.

AZD9496 is a potent and orally bioavailable selective estrogen receptor down regulator (Ki=0.7 nM) and antagonist.

B1652 | AZD9496 DataSheet

Alternate Name/Synonyms: AZD9496; AZD 9496; AZD-9496; (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic acid; (E)-3-[3,5-difluoro-4-[(1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]phenyl]prop-2-enoic acid

Appearance: Solid

Formulation: N/A

CAS Number: 1639042-08-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₅H₂₅F₃N₂O₂

Molecular Weight: 442.47

Cell-Permeable?: Yes

Purity: >98%

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A estrogen receptor inhibitor

MDL Number: NA

PubChem CID: 86287635

SMILES: CC1CC2=C(C(N1CC(C)(C)F)C3=C(C=C(C=C3F)C=CC(=O)O)F)NC4=CC=CC=C24

InChi: InChI=1S/C25H25F3N2O2/c1-14-10-17-16-6-4-5-7-20(16)29-23(17)24(30(14)13-25(2,3)28)22-18(26)11-15(12-19(22)27)8-9-21(31)32/h4-9,11-12,14,24,29H,10,13H2,1-3H3,(H,31,32)/b9-8+/t14-,24-/m1/s1

InChi Key: DFBDRVGWBHBJNR-BBNFHIFMSA-N