AZGP1 polyclonal Antibody | BS60269

AZGP1 polyclonal Antibody | BS60269 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: ZAG (Zn-a2-glycoprotein, also designated Zn-a2-gp) is a soluble, secreted protein found in serum and other body fluids (such as cerebrospinal fluid, blood plasma, urine and sweat) . ZAG has a tendency to precipitate with zinc salts, has electrophoretic mobility in the region of the two globulins, and has 18% carbohydrate content. A member of the immunoglobulin superfamily, ZAG has a high degree of sequence similarity to class-I major histocompatibility complex (MHC) antigens. The ZAG structure includes a large groove analogous to class I MHC peptide binding grooves. The crystal structure of ZAG resembles a class I MHC heavy chain but does not bind the class I light chain b-2-Microglobulin, unlike other MHC related proteins. ZAG stimulates lipid degradation in adipocytes and its overexpression causes the extensive fat losses associated with some advanced cancers.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: AZGP1 polyclonal Antibody detects endogenous levels of AZGP1 protein.

Molecular Weight: ~ 44 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Zinc-alpha-2-glycoprotein; Zn-alpha-2-GP; Zn-alpha-2-glycoprotein; AZGP1; ZAG; ZNGP1

Immunogen: A synthetic peptide corresponding to residues in Human AZGP1.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A