Azoramide | B3235

Azoramide is a small-molecule modulator of the unfolded protein response (UPR). It protects cells from ER stress by improving ER protein folding and activating ER chaperone capacity. Also improves ER calcium retention. Improves liver ER function, glucose homeostasis and glucose-stimulated insulin secretion in mouse obesity models. Displays antidiabetic activity.

Azoramide is a small-molecule modulator of the unfolded protein response (UPR). It protects cells from ER stress by improving ER protein folding and activating ER chaperone capacity. Also improves ER calcium retention. Improves liver ER function, glucose homeostasis and glucose-stimulated insulin secretion in mouse obesity models. Displays antidiabetic activity.

B3235 | Azoramide DataSheet

Alternate Name/Synonyms: N-[2-[2-(4-Chlorophenyl)-4-thiazolyl]ethyl]butanamide

Appearance: White solid

Formulation:

CAS Number: 932986-18-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₁₇ClN₂OS

Molecular Weight: 308.83

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities: >20 mg/ml Ethanol, >30 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A small-molecule modulator of the unfolded protein response (UPR)

MDL Number: MFCD08009374

PubChem CID: 7518316

SMILES: CCCC(=O)NCCC1=CSC(=N1)C2=CC=C(C=C2)Cl

InChi: InChI=1S/C15H17ClN2OS/c1-2-3-14(19)17-9-8-13-10-20-15(18-13)11-4-6-12(16)7-5-11/h4-7,10H,2-3,8-9H2,1H3,(H,17,19)

InChi Key: VYBFWKKCWTXCQX-UHFFFAOYSA-N