B2M Antibody (Ascites) [AMM22134G]

B2M Antibody (Ascites) [AMM22134G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H

Specificity: This B2M antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from human B2M.

Cellular Localisation: Secreted. Cell surface. Note=Detected in serum and urine (PubMed:1336137, PubMed:7554280) . {ECO:0000269|PubMed:7554280, ECO:0000269|Ref.6}

Molecular Weight: 13715

Clone: Monoclonal

Gene Name: B2M (HGNC:914)

Gene ID: 567

Function: Component of the class I major histocompatibility complex (MHC) . Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553) .

Summary: N/A

Form: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000~16000

Synonyms: Beta-2-microglobulin, Beta-2-microglobulin form pI 53, B2M