B3GALNT1 Antibody | 23-159

B3GALNT1 Antibody | 23-159 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 44-331 of human B3GALNT1 (NP_003772.1) .

Research Area: Other

Tested Application: WB, IF

Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: SKOV3

Positive Control 2: U-251MG

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 45kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: B3GALT3, GLCT3, GLOB, Gb4Cer, P, P1, beta3Gal-T3, galT3, UDP-GalNAc:beta-1, 3-N-acetylgalactosaminyltransferase 1, P antigen synthase, P blood group globoside, UDP-Gal:betaGlcNAc beta 1, 3-galactosyltransferase, polypeptide 3 (Globoside blood group) , UDP-GalNAc:betaGlcNAc beta-1, 3-galactosaminyltransferase, polypeptide 1 (Globoside blood group) , UDP-N-acetylgalactosamine:globotriaosylceramide beta-1, 3-N-acetylgalactosaminyltransferase, b3Gal-T3, beta-1, 3-GalNAc-T1, beta-1, 3-GalTase 3, beta-1, 3-galactosyltransferase 3, beta-3-Gx-T3, brainiac1, galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase, globoside synthase, globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene is a member of the beta-1, 3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine) . The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5) . The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all.