B3GNT5 Antibody (Center) [APR32721G]

B3GNT5 Antibody (Center) [APR32721G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This B3GNT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-145 amino acids from the Central region of human B3GNT5.

Cellular Localisation: Golgi apparatus membrane; Single- pass type II membrane protein

Molecular Weight: 44053

Clone: Polyclonal

Gene Name: B3GNT5 (HGNC:15684)

Gene ID: 84002

Function: Beta-1, 3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc (4) Cer; paragloboside), resulting in the synthesis of Lc (3) Cer and neolactopentaosylceramide (nLc (5) Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.

Summary: Tissue Location: Widely expressed. Highly expressed in lung, colon, placenta, testis, pituitary gland and cerebellum. Weakly expressed in brain, liver, spleen, lymph node and thymus

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Lactosylceramide 1, 3-N-acetyl-beta-D-glucosaminyltransferase, Lactotriaosylceramide synthase, Lc (3) Cer synthase, Lc3 synthase, UDP-GlcNAc:beta-Gal beta-1, 3-N-acetylglucosaminyltransferase 5, BGnT-5, Beta-1, 3-Gn-T5, Beta-1, 3-N-acetylglucosaminyltransferase 5, Beta3Gn-T5, B3GNT5