B4GalT1, soluble fragment, Human Recombinant | P1222

1,4-galactosyltransferase 1 was the first mammalian glycosyltransferase to be isolated and cloned. 4GalT1 is a member of a homologous family of seven 1,4-galactosyltransferases, 4Gal-T1 – T7, that catalyze the transfer of galactose from UDP-Gal to acceptor sugars including GlcNAc (the acceptor substrate for 4GalT1), Glc and Xyl. 4GalT1 exists as a membrane bound form and as a shed/secreted form deriving from proteolytic cleavage in the stalk region. 4GalT1 may form a heterodimer with -Lactalbumin, and the complex catalyzes the reaction of UDP-Gal + glucose -> lactose + UDP.

P1222 | B4GalT1 soluble fragment Human Recombinant DataSheet

Biomolecule/Target: B4GALT1

Synonyms: Beta-1,4-galactosyltransferase 1, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1, Beta-1,4-GalTase 1, Beta4Gal-T1

Alternates names: Beta-1,4-galactosyltransferase 1, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1, Beta-1,4-GalTase 1, Beta4Gal-T1

Taglines: Catalyze the transfer of galactose from UDP-Gal to acceptor sugars

NCBI Gene ID #: 843

NCBI Gene Symbol: CASP10

Gene Source: Human

Accession #: Q92851

Recombinant: Yes

Source: Insect cells

Purity by SDS-PAGEs: 90%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): Measured by transfer of galactose from UDP-galactose (UDP-Gal) to 4-Methylumbelliferyl N-acetyl--D-glucosaminide.

Biological activity: Specific activity >2,500 pmol/min/mg

Results: >2,500 pmol/min/mg

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 35 kDa

Concentration: 440 ug/ml

Appearance: Liquid

Physical form description: Sterile filtered solution in 25 mM Tris pH 7.5 and 150 mM NaCl

Reconstitution Instructions: N/A

Amino acid sequence: N/A