B4GALT4 Antibody (Center) [APR15120G]

B4GALT4 Antibody (Center) [APR15120G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This B4GALT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-117 amino acids from the Central region of human B4GALT4.

Cellular Localisation: Golgi apparatus, Golgi stack membrane; Single- pass type II membrane protein. Note=Trans cisternae of Golgi stack

Molecular Weight: 40041

Clone: Polyclonal

Gene Name: B4GALT4 {ECO:0000303|PubMed:17690104, ECO:0000312|HGNC:HGNC:927}

Gene ID: 8702

Function: Galactose (Gal) transferase involved in the biosynthesis of glycoproteins, proteoglycans, and glycosyphingolipids (PubMed:9792633, PubMed:17690104) . Catalyzes the transfer of Gal residue via a beta1->4 linkage from UDP-Gal to the non-reducing terminal N-acetyl glucosamine 6-O-sulfate (6-O-sulfoGlcNAc) in the linearly growing chain of both N- and O-linked keratan sulfate proteoglycans. Cooperates with B3GNT7 N-acetyl glucosamine transferase and CHST6 and CHST1 sulfotransferases to construct and elongate mono- and disulfated disaccharide units [->3Galbeta1->4 (6-sulfoGlcNAcbeta) 1->] and [->3 (6-sulfoGalbeta) 1->4 (6- sulfoGlcNAcbeta) 1->] within keratan sulfate polymer (PubMed:17690104) .

Summary: Tissue Location: Highest expression is observed in placenta, pancreas, kidney and heart (PubMed:9792633) . Expressed in corneal epithelial cells (PubMed:17690104) .

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Beta-1, 4-galactosyltransferase 4, Beta-1, 4-GalTase 4, Beta4Gal-T4, b4Gal-T4, 241-, UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 4, UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 4, N-acetyllactosamine synthase, Nal synthase, Lactotriaosylceramide beta-1, 4-galactosyltransferase, Beta-N-acetylglucosaminyl-glycolipid beta-1, 4-galactosyltransferase, B4GALT4