B4GALT5 Antibody (C-term) [APG02156G]

B4GALT5 Antibody (C-term) [APG02156G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This B4GALT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-350 amino acids from the C-terminal region of human B4GALT5.

Cellular Localisation: Golgi apparatus, Golgi stack membrane {ECO:0000250|UniProtKB:P15291}; Single-pass type II membrane protein Golgi apparatus {ECO:0000250|UniProtKB:A0A1S6M251}. Note=Trans cisternae of Golgi stack. {ECO:0000250|UniProtKB:P15291}

Molecular Weight: 45119

Clone: Polyclonal

Gene Name: B4GALT5 (HGNC:928)

Gene ID: 9334

Function: Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) (PubMed:24498430) . LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity) . Plays a role in the glycosylation of BMPR1A and regulation of its protein stability (By similarity) . Essential for extraembryonic development during early embryogenesis (By similarity) .

Summary: Tissue Location: Ubiquitously expressed.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, FC

Dilution: WB--1:1000 FC--1:10~50

Synonyms: Beta-1, 4-galactosyltransferase 5, Beta-1, 4-GalTase 5, Beta4Gal-T5, b4Gal-T5, 241-, Beta-1, 4-GalT II, UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 5, UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 5, B4GALT5