B4GALT6 polyclonal Antibody | BS60629

B4GALT6 polyclonal Antibody | BS60629 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB

Application Range: WB: 1:500~1:1000

Background: β-1,4-galactosyltransferases (β-1,4-Gal-T) are type II membrane-bound glycoproteins that are substrate-specific and function to transfer galactose in a β-1,4 linkage to an acceptor sugar. There are seven members of the β-1,4-Gal-T family, all of which are directed to the Golgi apparatus through a hydrophobic sequence at the N-terminus. β-1,4-Gal-T6, also known as B4GALT6, is a 382 amino acid single-pass type II membrane protein that localizes to the Golgi apparatus and belongs to the β-1,4-galactosyltransferase family. Expressed at high levels in adrenal gland and brain and present at lower levels in lung, liver and colon, β-1,4-Gal-T6 uses magnesium or zinc to catalyze the UDP-dependent biosynthesis of glycosphingolipids. The gene encoding β-1,4-Gal-T6 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: B4GALT6 polyclonal Antibody detects endogenous levels of B4GALT6 protein.

Molecular Weight: ~ 45 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Beta-1,4-galactosyltransferase 6; Beta-1,4-GalTase 6; Beta4Gal-T6; b4Gal-T6; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6 ; Including the following 1 domains:Glucosylceramide beta-1,4-galactosyltransferase; Lactosylceramide synthase; LacCer synthase; UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase; B4GALT6

Immunogen: A synthetic peptide corresponding to residues in Human B4GALT6

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: