B4GALT7 Antibody | 19-396

B4GALT7 Antibody | 19-396 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: A synthetic Peptide of human B4GALT7

Research Area: Cancer, Cell Cycle, Signal Transduction

Tested Application: WB

Application: WB: 1:500 - 1:1000

Specificiy: N/A

Positive Control 1: Human pancreas

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 37kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, pH7.3.

Concentration: N/A

Storage Condition: Store at 4˚C. Avoid freeze / thaw cycles.

Alternate Name: EDSP1, EDSSLA, EDSSPD1, XGALT1, XGPT, XGPT1, beta-1, 4-galactosyltransferase 7, UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 7, UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 7, UDP-galactose:beta-xylose beta-1, 4-galactosyltransferase, beta-1, 4-GalTase 7, beta-1, 4-galactosyltransferase VII, beta4Gal-T7, beta4GalT-VII, galactosyltransferase I, proteoglycan UDP-galactose:beta-xylose beta1, 4-galactosyltransferase I, xylosylprotein 4-beta-galactosyltransferase, xylosylprotein beta 1, 4-galactosyltransferase, polypeptide 7, xylosylprotein beta-1, 4-galactosyltransferase

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene is a member of the beta-1, 4-galactosyltransferase (beta4GalT) family. Family members encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose. Each beta4GalT member has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus which then remains uncleaved to function as a transmembrane anchor. The enzyme encoded by this gene attaches the first galactose in the common carbohydrate-protein linkage (GlcA-beta1, 3-Gal-beta1, 3-Gal-beta1, 4-Xyl-beta1-O-Ser) found in proteoglycans. This enzyme differs from other beta4GalTs because it lacks the conserved Cys residues found in beta4GalT1-beta4GalT6 and it is located in cis-Golgi instead of trans-Golgi. Mutations in this gene have been associated with the progeroid form of Ehlers-Danlos syndrome.