B7-H3/CD276 Polyclonal Antibody | E-AB-64054

B7-H3/CD276 Polyclonal Antibody | E-AB-64054 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CD276, 4Ig-B7-H3, B7-H3, B7H3, B7RP-2

Application: WB

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Immunology, Stem Cells

Background: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: A synthetic peptide of human B7-H3/CD276 (NP_001019907.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 33 kDa/52 kDa/57 kDa

Molecular Weight(Observed): 115 kDa