BACE1 Antibody [3C1C3] | 32-238

BACE1 Antibody [3C1C3] | 32-238 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Rurified recombinant fragment of human BACE1 (AA: 112-324) expressed in E. Coli.

Research Area: Neuroscience

Tested Application: E, WB, ICC, Flow

Application: ELISA: 1/10000
Western Blot: 1/500 - 1/2000
ICC: 1/200 - 1/1000
Flow Cytometry: 1/200 - 1/400

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: 3C1C3

Isotype: IgG1

Conjugate: Unconjugated

Physical State: N/A

Buffer: Purified antibody in PBS with 0.05% sodium azide.

Concentration: N/A

Storage Condition: BACE monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: BACE Antibody: ASP2, BACE, HSPC104, KIAA1149, Beta-secretase 1, Aspartyl protease 2, ASP2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.