Bafetinib | B1172

Bafetinib (INNO-406) is a potent and selective dual Bcr-Abl, Lyn inhibitor with IC₅₀ values of 5.8 nM and 19 nM, respectively.

Bafetinib (INNO-406) is a potent and selective dual Bcr-Abl, Lyn inhibitor with IC₅₀ values of 5.8 nM and 19 nM, respectively.

B1172 | Bafetinib DataSheet

Alternate Name/Synonyms: N-[3-([4,5’-Bipyrimidin]-2-ylamino)-4-methylphenyl]-4-[[(3S)-3-(dimethylamino)-1-pyrrolidinyl]methyl]-3-(trifluoromethyl)benzamide; INNO 406; NS 187

Appearance: Yellow solid

Formulation: N/A

CAS Number: 859212-16-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₃₀H₃₁F₃N₈O

Molecular Weight: 576.62

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and selective dual Bcr-Abl, Lyn inhibitor

MDL Number: N/A

PubChem CID: 11387605

SMILES: CC1=C(C=C(C=C1)NC(=O)C2=CC(=C(C=C2)CN3CCC(C3)N(C)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CN=C5

InChi: InChI=1S/C30H31F3N8O/c1-19-4-7-23(13-27(19)39-29-36-10-8-26(38-29)22-14-34-18-35-15-22)37-28(42)20-5-6-21(25(12-

InChi Key: ZGBAJMQHJDFTQJ-DEOSSOPVSA-N