Description
BAG6 Antibody | 18-444 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human BAG6 (NP_001092004.1) .
Research Area: Apoptosis, Cancer, Cell Cycle
Tested Application: WB
Application: WB: 1:500 - 1:2000
Specificiy: N/A
Positive Control 1: 293T
Positive Control 2: HeLa
Positive Control 3: Mouse testis
Positive Control 4: Rat testis
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 160kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: scythe, large proline-rich protein BAT3, HLA-B associated transcript-3, G3, D6S52E, BAG6, BAG-6, HLA-B associated transcript 3, BAT3
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.