Baicalein | B2309

A potent inhibitor of 5- and platelet 12-lipoxygenases (IC50 values are 9.5 and 0.12 μM respectively). Baicalein inhibits lipid peroxidation, as assessed by production of thiobarbituric acid (TBARS; IC₅₀= 5 µM), and inhibits growth of Huh-7, KIM-1, and HLF human hepatocellular carcinoma cells (IC₅₀s = 17-70 µg/ml).

Baicalein is a potent inhibitor of 5- and platelet 12-lipoxygenases (IC50 values are 9.5 and 0.12 μM respectively). Baicalein inhibits lipid peroxidation, as assessed by production of thiobarbituric acid (TBARS; IC₅₀= 5 µM), and inhibits growth of Huh-7, KIM-1, and HLF human hepatocellular carcinoma cells (IC₅₀s = 17-70 µg/ml).

B2309 | Baicalein DataSheet

Alternate Name/Synonyms: 5,6,7-Trihydroxy-2-phenyl-(4H)-1-benzopyran-4-one

Appearance: Yellow solid

Formulation: N/A

CAS Number: 491-67-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₁₅H₁₀O₅

Molecular Weight: 270.24

Cell-Permeable?:

Purity: ≥98%

Solubilities: DMSO (>10 mg/ml)

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent inhibitor of 5- and platelet 12-lipoxygenases

MDL Number: MFCD00017459

PubChem CID: 5281605

SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)O)O)O

InChi: InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H

InChi Key: FXNFHKRTJBSTCS-UHFFFAOYSA-N