Description
BAK1 Polyclonal Antibody | E-AB-10092 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: Apoptosis regulator BAK, BAK, BAK like, Bak NT, BAK, Bak1, Bcl 2 homologous antagonist/killer, Bcl 2 like 7 protein, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 7, BCL2 antagonist/killer 1, Bcl2 like 7 Protein, Bcl2-L-7, BCL2L7, CDN1, Cell death inhibitor 1, MGC117255, MGC3887, NBak, Pro apoptotic protein BAK
Application: WB, IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology
Background: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Concentration: 0.3 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human BAK1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 23 kDa
Molecular Weight(Observed): N/A